Ask Ausiello: Spoilers on 'Gossip Girl,' 'Grey's,' 'Big Bang,' 'Lost,' 'NCIS,' '90210,' and more!

Question: This two-week Lost hiatus is killing me! More scoopage before the final episodes, please! –Brad

Ausiello: The major-ish Lost death is coming up soooooon. Also, it’s less ish and more major than I first thought.

Question: Please, please, please give us a hint about whom Sylar kills in Monday’s Heroes season finale! –Claire

Ausiello: It’s a major character, and the death definitely sticks. But there is a twist. (Hint: It’s possible no one will be leaving the show.) BTW, the finale is fantastic. It’s compelling, suspense-filled and, most importantly, events occur consecutively and in the present day. Heroes is back, people!

Question: Any more Big Bang Theory scoop for the finale? –Hannah

Ausiello: It’s going to be full of crap! Kaley Cuoco explains: “The [guys] build a toilet and things go horribly wrong. They all find poop hilarious. It’s a space toilet, so I don’t have to use it or anything. Of course, it’s a space toilet on this show!” On the hotly debated subject of a Penny-Sheldon hookup, Cuoco confesses that she’s not a fan of the idea. “I don’t think it makes any sense,” she says. “Sheldon has no use for women. If it happened, I bet it would be a nightmare sequence. Sheldon is nowhere near boyfriend material and Penny loves him that way. [Besides], Sheldon barely lets her into his apartment — how would he get to the point of hooking up with her?”

Question: Your single-topic AA on Grey’s gave us nothing on the best couple, Meredith and Derek! Please, can you give us something juicy? — Hayley

Ausiello: Okay, here’s something: A longtime Grey’s duo are about to break up — presumably for good — and it’s not Derek and Meredith. Nope. It’s Bailey and Tucker! In the May 14 season finale, Bailey takes the bold step of leaving her husband after he once again fails to support her career.

Question: Can you tell us how much time has lapsed between the elevator proposal episode of Grey’s and the episode that airs this week? –Jasmin

Ausiello: A few days, I believe. It’s not long at all.

Question: I’ve decided that I want your job. May I ask, how good is the pay? –Saramarie

Ausiello: Where I come from, it’s tacky to discuss such things in public. It’s not, however, tacky to show you a picture of the second home I just purchased in the Hamptons and let you draw your own conclusions.

Question: Any scoop on the anticipated Thatcher return on Grey’s next week? I’m hoping for some overdue Meredith and Lexie scenes! –Dana

Ausiello: Two of my favorite Mer-Lexie scenes ever take place in next week’s episode, but it’s more a result of the thorny Derek-Mark situation than Thatcher’s return.

Question: Any insight on what is going to happen with Mer-Der now that Ellen Pompeo is preggers in real life? –R Aliberti

Ausiello: If you’re asking me whether there’s a McBaby in their future, I don’t know. I can tell you that if Pompeo takes the standard two-month maternity leave following the birth of her first child this fall, Grey’s could be Mer-less for a portion of next season. Maybe they’ll send her to some really long medical convention. Or dispatch her to the parking lot to look for Dr. Hahn. The possibilities are endless!

Question: Will Jeffrey Dean Morgan be appearing in Grey’s Anatomy’s 100th episode? –Javier

Ausiello: Let’s examine the evidence, shall we? Exhibit A: Morgan appeared in the 100th ep photo-op, which took place on the Grey’s set during filming of the said 100th episode. Exhibit B: The official logline for the landmark ep says, “Izzie fears the worst when she begins experiencing familiar symptoms.” Exhibit C: I have to warn you that this one’s really spoilery, but I’m hearing … wait, what’s that? The jury of Ausholes has already reached a unanimous verdict? Eh, so much for my Exhibit C. It was really good, too.

Question: Please give us some more dish on Law & Order: SVU‘s death mystery! –Bri

Ausiello: I doubt there will be many fans mourning this person’s passing. I’ll leave it at that.

Question: Any advance scoop on Glee? The commercials alone make me smile. –Chris

Ausiello: I’m in love with the commercials. I want to marry the commercials. I want to have babies with the commercials. Unfortunately, I only want to date the actual show. That’s right, the revised pilot for the program I’ve been prematurely raving about for months recently fell on my lap and, well, it didn’t exactly wow me. The good news: There’s more tweaking going on that may address some of my complaints — most of which concern the schizophrenic pacing and tone. Bottom line: There’s an awesome show in there somewhere and I’m praying Ryan Murphy finds it by May 19. And if not by May 19, then by next fall when it returns.

Question: Any scoop on who is going to die on CSI: NY? Is it someone shown in the opening credits? — Carissa

Ausiello: Yes. And as exec producer Pam Veasey reveals, in addition to the death “something happens to someone else. There will be a life-changing experience for another character.” Veasey declined to say whether that something was good or bad, although she did offer what could be a clue: “We really want to have a hopeful and heroic start to next season. It’ll be really positive, fun, and spirited.”

Question: I’m happy Lindsay’s returning to CSI: NY next month, but do we know for a fact Anna Belknap ever gave birth? I searched high and low on the Interwebs but I can’t find any info about it. –Claire

Ausiello: That’s probably because there’s no info to be found — until now! Sources confirm to me exclusively that Anna gave birth to her second child, son George, on Feb. 6. (You’re welcome, Google.)

Question: 24 scoop, please! –Matt

Ausiello: Chloe returns next week! Woo-hoo! And she’s forced to work alongside Janice! Double woo-hoo!

Question: You said that NCIS fans shouldn’t be worried about Michael Weatherly leaving, so tell me straight out: Is Cote de Pablo leaving the show? — Jillian

Ausiello: All exec producer Shane Brennan would tell me is that the season ends “on a cliff, not so much a hanger.” Um, huh? “It’s an episode that will compel people to come back for the first episode next season,” he elaborates. “They will have to come back and watch what happens in the first episode next season because of what we do at the very end of this season. We’ve already worked out what that episode is. We’ve got a fantastic season opener that is set up in the finale. The thing about the opener for next season is, once again, your expectations of what you think you’re going to see will be turned on their head with the season premiere. I’m a great believer in tying the audience in knots over the summer. It’ll have people arguing whether it was a good thing or a bad thing and what the outcome will be.” Still a little confused about the difference between a cliff and a hanger, but I’m admittedly not the brainiest Smurf in the village.

Question: Got anything on Psych? –Sean

Ausiello: I’ve got the first significant piece of guest casting for season 4! In an early eppy, Christine Baranski will play Alice Clayton, the well-maintained widow of a billionaire hedge fund manager who believes her husband’s death in a plane crash was not accidental, but murder.

Question: Here is my weekly request for some Private Practice scoop. –Stacey

Ausiello: Prepare yourselves for the most disturbing childbirth scene since Jessica Lange forced Gwyneth Paltrow to deliver her baby via an oxytocin-laced layer cake in 1998’s Hush.

Question: Got any information on the upcoming season of Weeds? –Brandon

Ausiello: I’m hearing Silas is going to take on a partner to help run his little business.

Question: 90210 has turned a corner. I’m hooked. Scoop, please. –Tiffany

Ausiello: It’s so bad it’s awesome, right? Here’s a little big scooplet: Liam will sleep with someone in the finale … and it’s not Naomi! (Or *****!)

Question: Any chance Dustin Milligan will return to 90210 to wrap up his story next season? –Ian

Ausiello: No. He will not be back.

Question: I read somewhere that the season finale of Gossip Girl includes Serena uncovering the identity of GG. Will she be successful? –Mike

Ausiello: She uncovers the identity of someone connected to GG, but not GG herself.

Question: I need Gossip Girl scoop, preferably about the prom. –Lindsay

Ausiello: Revenge-seeking Chuck, furious at Blair for attending the big ball with Nate, hatches a plan to make Nelly Yuki prom queen. Meanwhile, Dan and Serena end up going together, but as friends, not lovers.

Question: Please give some good Desperate Housewives scoops! Is it true that Bree is going to have an affair with Karl? –Martin

Ausiello: Can’t confirm an affair. Can confirm a kiss.

Question: Are Mike and Susan ever going to get back together on Desperate Housewives? I’m really thinking of tanking the show next year if not. Give us some good news, please! –Nadine

Ausiello: James Denton and Teri Hatcher told us at PaleyFest ’09 that it’s “inevitable” the two will reunite, but neither had specifics on when. “It’s always been Marc Cherry’s plan to have them together by the end of the show,” said Hatcher. “But I think the road getting there is getting bumpier and bumpier.” Added Denton: “I think there will definitely be at least another near miss for them, but for the rest of the season and the near future, it is Mike and Katherine. They are getting pretty secure. We are already living together. And I think there may be some engagement news on the horizon.”

Question: I haven’t heard anything on Greek in a while. Any scoop? –Jaclyn

Ausiello: “The finale has a really good cliffhanger,” Scott Michael Foster (Cappie) revealed at Saturday’s GLAAD Awards in Los Angeles. “And Jesse McCartney plays a really big part of that cliffhanger. It has a lot to do with him and Rusty …. I guess I get some action, too. In my women’s studies class I’m the only guy, so the ladies are like sitting ducks. Of course, he will always be at least partly stuck on Casey.” What’s Casey doing while Cappie’s getting busy? She’s getting busy herself! “She gets a lot of action … from multiple sources,” confirmed Spencer Grammer. “Cappie is her soul mate, but she’s young and she doesn’t always see that.”

Question: Got anything on the Supernatural finale that you don’t have to block out with hundreds of asterisks? –David

Ausiello: Comic book geek-slash-prophet Chuck will be back! See, no asterisks!

Okay, that’s a wrap! Send questions-anonymous tips-housewarming gift certificates to ausielloscoop@ew.com Thanks for playing! (Additional reporting by Carrie Bell)