See Grey's Antomy's Ellen Pompeo, Jesse Williams, Camilla Luddington in EW cover shoot photos

01 of 11

Ellen Pompeo (Dr. Meredith Grey)

ga_ep_1278y21782182189 — James White for EW

Pompeo not only headlines the ABC show but helps to produce the mega-hit, too. "I'm very fortunate that I actually get to see how my presence directly impacts the money the show makes," Pompeo says proudly.

02 of 11

Jesse Williams (Dr. Jackson Avery) and Kelly McCreary (Dr. Maggie Pierce)

ga_jw_1289922010112 — James White for EW

Finally, it's their turn this season. "Maggie and Jackson are exploring love they have finally claimed," teases executive producer Krista Vernoff.

03 of 11

James Pickens Jr. (Dr. Richard Webber) and Chandra Wilson (Dr. Miranda Bailey)

ga_cb_1221829819821892189 — James White for EW

"I dig the fans," Pickens says. "If it weren't for the fans, we wouldn't be celebrating 15 right here. Different actors have different takes on fans and what fans quote unquote require of them. I think it's a privilege that we've impacted their lives to such an extent that they have been willing to take this journey, right now going into our 15th season."

04 of 11

Justin Chambers (Dr. Alex Karev) and Camilla Luddington (Dr. Jo Wilson)

ga_jc_238792210210921-021 — James White for EW

Chambers still remembers how he felt while shooting the Grey's pilot. "Nerves, definitely nerves," he recalls. "I was with all these other actors, I didn't know anybody, and I was hoping the show would be a success and thank God it worked out." Luddington, who came much later, spent her first day "geeking out" in Meredith's house "when I wasn't supposed to be there. We weren't even shooting and I just kind of crept on and investigated everything, because I was a fan of the show. So my first memories of being on set was even before we started filming anything and I was sneaking into Meredith's house."

05 of 11

Kim Raver (Dr. Teddy Altman), Kevin McKidd (Dr. Owen Hunt), and Caterina Scorsone (Dr. Amelia Shepherd)

ga_km_27278182189210921 — James White for EW

Gird your loins, Grey's fans. These three are about to bring a whole lot of drama to Grey Sloan Memorial. "Owen and Teddy and Amelia have what I think is a very complicated love triangle this season," teases Vernoff.

06 of 11

Collector's Cover #1: Ellen Pompeo (Dr. Meredith Grey)

ew1530_ep_2387329389232 — James White for EW

EW is celebrating #7DaysofGreys! For more on Grey’s Anatomy, pick up the new issue of Entertainment Weekly on stands Friday, or buy Meredith Grey's cover now.

07 of 11

Collector's Cover #2: Justin Chambers (Dr. Alex Karev) and Camilla Luddington (Dr. Jo Wilson)

ew1530_jc_328732983289239 — James White for EW

EW is celebrating #7DaysofGreys! For more on Grey’s Anatomy, pick up the new issue of Entertainment Weekly on stands Friday, or buy Alex and Jo's cover now.

08 of 11

Collector's Cover #3: Kelly McCreary (Dr. Maggie Pierce) and Jesse Williams (Dr. Jackson Avery)

ew1530_jw_323726832483323 — James White for EW

EW is celebrating #7DaysofGreys! For more on Grey’s Anatomy, pick up the new issue of Entertainment Weekly on stands Friday, or buy Avery and Pierce's cover now.

09 of 11

Collector's Cover #4: James Pickens Jr. (Dr. Richard Webber) and Chandra Wilson (Dr. Miranda Bailey)

ew1530_278271982101202121 — James White for EW

EW is celebrating #7DaysofGreys! For more on Grey’s Anatomy, pick up the new issue of Entertainment Weekly on stands Friday, or buy Bailey and Webber's cover now.

10 of 11

Collector's Cover #5: Kim Raver (Dr. Teddy Altman), Kevin McKidd (Dr. Owen Hunt), and Caterina Scorsone (Dr. Amelia Shepherd)

ew1530_km_2872137892102103 — James White for EW

EW is celebrating #7DaysofGreys! For more on Grey’s Anatomy, pick up the new issue of Entertainment Weekly on stands Friday, or buy Altman, Hunt, and Shepherd's cover now.

11 of 11

Collector's Cover #6: Rushi Kota (Dr. Vik Roy), Alex Blue Davis (Dr. Casey Parker), Sophia Ali Taylor (Dr. Dahlia Qadri), Giacamo Gianniotti (Dr. Andrew DeLuca), Jake Borelli (Dr. Levi Schmitt), and Jaicy Elliot (Dr. Taryn Helm)

ew1530_2118721892819301200 — James White for EW

EW is celebrating #7DaysofGreys! For more on Grey’s Anatomy, pick up the new issue of Entertainment Weekly on stands Friday, or buy the cover of DeLuca and the interns now.

See all the stunning photos from EW's Grey's Anatomy cover shoot