The ladies have spoken!  After four weeks of voting, historic Santa Fe, New Mexico has landed in the sweet spot.  It's the number one destination for a ladies trip, according to readers of USA TODAY and 10Best.  

New Mexico's amazing capital city is a popular ski destination in winter, but Santa Fe is lovely (and cool) in summer.  Memories of a lifetime are also made during fall in this gorgeous high desert location that's a Mecca for artists.  Fine art galleries abound, as do newsworthy restaurants, welcoming hotels, terrific spas, great shopping, live music and the opportunity to explore a history that stems from four distinct cultures.  

Georgia O'Keefe Museum is a highlight for many female visitors.  The best part?  Once you arrive, no car is really required.   Even the Santa Fe Opera is only a short cab ride from downtown's famed Plaza, which is ringed by hotels. 

Lovely Charleston, with its abundance of spring flora, gorgeous architecture, world-class food and gracious residents, took second place.  Tuscany - even more beloved since Under the Tuscan Sun  - took a solid third.  California's Carmel by the Sea and teh always entertaining Nashville round out our top five winners.   

Three major metros were voted into the top 10, and two more southern cities (one east, one west) drew the remainder of votes from our female audience.  

The full list of winners in the 'Best Girls' Trip' contest category for 10Best Readers' Choice is: