Satyanarayan H.

Gainesville, Florida, United States Contact Info
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I am a dedicated Pediatric Pulmonologist, Researcher, and Healthcare Innovator passionate…

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  • Doctor, Make My Asthma Better!

    Poster Presentation, Presenting Author at American Thoracic Society International Conference, Denver, May 2015

  • Optimizing an Internal Airway Percussion Device for Facilitating Exhalate Diagnostics of the Human Respiratory System

    Journal of Aerosol Medicine and Pulmonary Drug Delivery (submitted)

    Purpose: The diagnosis of pulmonary infections requires techniques that are inexpensive, direct, repeatable, and non-invasive.An inexpensive, direct, repeatable and non-invasive technique is a demonstrated need for pulmonary infection diagnosis. This study seeksaimed to develop and optimize a novel technique of Internal Airway Percussion (IAP) to facilitate the collection and charicterization of exhalate diagnostics of the human respiratory system exhalates.
    Methods: The IAP device transmits…

    Purpose: The diagnosis of pulmonary infections requires techniques that are inexpensive, direct, repeatable, and non-invasive.An inexpensive, direct, repeatable and non-invasive technique is a demonstrated need for pulmonary infection diagnosis. This study seeksaimed to develop and optimize a novel technique of Internal Airway Percussion (IAP) to facilitate the collection and charicterization of exhalate diagnostics of the human respiratory system exhalates.
    Methods: The IAP device transmits acoustic sound waves into the respiratory airway tract,s vibratingfor effective vibration of the lungs and increasingto increase the release of aerosolized particles withininto the exhaled breath. Before-and-after pair trials were conducted as sensitivity analysis on Ninenine combinations of sound wave frequencies and amplitudes were compared to determine optimum sensitivity of IAP frequency and amplitude of the IAP from used with healthy human subjects.
    Results: SThe results showed that square-shaped sound waves generated at 15 Hz and 3 cm H2O provided increased thethe most effective performance for the device. Mean increase of 15 times in total mass of collected particles in the first 2 min of sampling, and increased the count median diameter of exhaled particles by 1.2 to 1.5 times. increase in count median diameter of the particles were obtained at the optimal operational condition.
    Conclusions: The optimized IAP, optimized at 15 Hz and 3 cm H2O, proposed in this tudy was successful in significant increased the in total mass of exhaled bio-particles exhaled from the human respiratory system. The optimized IAP device has a broad range of potential clinical applications for non-invasive diagnosis of lung diseases including asthma, cystic fibrosis, pneumonia and lung cancer along with improvement of mucus clearance.

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