This range is provided by Vevo Therapeutics. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.
Base pay range
$120,000.00/yr - $145,000.00/yr
About Us We are a biotechnology company based in San Francisco. We are using our in vivo drug discovery platform and AI models trained on its data to uncover better drugs for more patients. Our Mosaic platform is the first to make in vivo data generation scalable, with single-cell precision, to capture in vivo context of disease at the first step of drug discovery and to better represent patient diversity in drug response over current in vitro assays. We are using Mosaic to build the world’s largest in vivo atlas of how drugs interact with patient cells and how they alter gene function in diverse biological contexts. We are using the unprecedented scale and sophistication of the data in this atlas to train single-cell foundation models that learn context dependency of gene function and help us find novel targets and drugs that are more likely to work in patients. Your Role At Vevo, we generate a huge amount of data on how drugs interact with cells from many different patients, at a single-cell resolution and in an in-vivo context. All of this data originates in house using our Mosaic platform that allows us to test hundreds of drugs on tens to hundreds of patients in a single mouse or organoid. We are seeking a scientist with deep expertise in single-cell RNA sequencing and spatial methods, scaling complex biological assays, and oncology research background. You will be part of our experimental team, with the responsibility to lead Mosaic experiments, develop the next generation of the platform using novel readout modalities and input types, and generate the multi-million cell atlases that discover our novel therapeutic programs. You will also work closely with the bioinformatics team. Qualifications - Required
In-depth and hands–on experience in single-cell RNA sequencing methods and method development in this space
In-depth and hands–on experience in scaling compound or bioassay screening operations and training others
Deep oncology research background
In-depth and hands–on experience in NGS method development for platform improvements and new readouts and experience in bioinformatics analysis
Experience and familiarity in building out oncology stories by interpreting single-cell atlas data, generating knockdown/out lines, and assessing efficacy using dose-response, in-vivo xenograft, and biochemical assays in an oncology setting
Experience in a fast paced environment and ability to work quickly to achieve company goals
Ph.D in relevant discipline required
Qualifications - Desirable
Experience in transitioning single-cell assays to spatial methods
Experience in taking drug candidates to IND
Postdoc and industry experience are strongly desired
Key Responsibilities
Leading and executing single-cell RNA data generation efforts at Vevo
NGS method development for platform improvements and new readouts
Generation of insights for new oncology programs using Vevo’s Mosaic platform
Scaling the Mosaic bioassay for generation of large scale Mosaic Atlases
Benefits
Unlimited Paid Time Off (PTO)
Monthly Lunch budget
One-time Office set up budget
US Employees: HMO Kaiser Platinum and PPO Anthem Gold medical as well as vision and dental plans for both the employee and dependents
Seniority level
Not Applicable
Employment type
Full-time
Job function
Health Care Provider
Industries
Biotechnology Research
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