#EHA2024 presentation recap: median overall survival of 5.49 months observed in patients with a TP53 mutation receiving an Iomab-B led allogeneic #bonemarrowtransplant compared to 1.66 months in patients that did not receive Iomab-B in Phase 3 SIERRA Trial. More details here: https://lnkd.in/gBJF3HT3
Actinium Pharmaceuticals, Inc.’s Post
More Relevant Posts
-
📣 A new preprint from Team Chen focuses on understanding the role of LRRK2 G2019S mutation on helper T-Cell function and how that impacts PD #pathogenesis. https://bit.ly/4b4CrOr
To view or add a comment, sign in
-
Molecular glues and bifunctional compounds: Therapeutic modalities based on induced proximity This Perspective explores molecular glues and bifunctional compounds—proximity-inducing compounds—and offers a framework to understand and exploit their similarity to hotspots, missense mutations, and posttranslational modifications (PTMs). https://lnkd.in/gQkcQhZz
To view or add a comment, sign in
-
Living with EGFR mutation? Consider enrolling in a clinical trial today. Learn more: https://lnkd.in/dG56u2zT #NSCLC #EGFRpositive #nonsmallcelllungcancer #lungcancer #ClinicalTrials #PatienTrials
To view or add a comment, sign in
-
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations https://lnkd.in/gshevWSr
To view or add a comment, sign in
-
Factor V, Factor II, Factor XIII, MTHFR, and PAI-1 are conditions that increase the chances of experiencing blood clots for people all around the world. While conditions can be acquired, many are genetic and inherited. GeneProof PCR kits follow an easy-to-use concept, simple laboratory workflow, and are compatible with a wide range of real-time PCR devices. To learn more about GeneProof a.s. comprehensive portfolio of Thrombotic Mutation PCR kits visit: bit.ly/3FpGqaE #Thrombosis #ThromboticMutations #GeneProof
To view or add a comment, sign in
-
High-fidelity Taq DNA ligase is now available! This product has been obtained through protein mutation, significantly reducing mismatched ligation, making it particularly suitable for molecular diagnostic applications based on nicked-pair ligation, such as LCR (Ligase Chain Reaction), LDR (Ligation Detection Reaction), and MLPA (Multiplex Ligation-dependent Probe Amplification).
To view or add a comment, sign in
-
#essentialthrombocythemia patients with the #CALR exon 9 mutation are less likely to require cytoreductive therapy, such as hydroxyurea, compared to those with #JAK2 mutations. Cytoreductive therapy helps control platelet levels, reducing the risk of clotting events.
To view or add a comment, sign in
-
Improving cellular phylogenies through the integrated use of mutation order and optimality principles. Read the article here: https://lnkd.in/d2RvWCVu
Improving cellular phylogenies through the integrated use of mutation order and optimality principles
sciencedirect.com
To view or add a comment, sign in
-
Yup. E. coli LPS (2) has the PPi binding site for #clovibactin, but you need enough (no asmB1 mutation) for clov oligomerization, whereas H. influenzae LPS (3) lacks the binding site. E. coli LPS is probably occupying clovibactin and preventing its action on its intended target. https://lnkd.in/g8ZKUHCJ
To view or add a comment, sign in
-
Consultant Internal Medicine(MD)/SMSB MRCP1/MRCP2, DHA/MOH holder. Uptodate Medcare Centre Dubai/UAE
Mitapivat is a new treatment that is being tested in people with alpha thalassemia or BT. It’s a tablet that you take twice a day. It’s already used to treat another genetic condition, called pyruvate kinase deficiency. Mitapivat increases the level of an enzyme that red blood cells need to function properly. This enzyme is low in thalassemic red blood cells. Early trial results show that mitapivat may help to reduce anemia in people with BT who don’t need regular blood transfusions. Side effects found so far include difficulty sleeping, headache and dizziness. Mitapivat is being tested in phase III trials for people with BT who don’t need regular transfusions, as well as those who do.
To view or add a comment, sign in
12,797 followers