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View profile for Kristin Baier MD, graphic

Innovative Healthcare Leadership | Obesity Medicine Physician | Lifestyle Advocate

"In patients treated with semaglutide, weight loss continued over 65 weeks and was sustained for up to 4 years." In addition to what appears to be cardiovascular protective effects from semaglutide before weigh loss even occurs, it's incredibly exciting to see these results as we know the recidivism rate in weight loss is extremely high. It also highlights the importance of combining GLP medication with intensive lifestyle interventions for optimal outcomes. This SELECT trial had a lower average weight loss (mean 10.2% at 208 weeks) than the STEP trials (mean 14.9% at 68 weeks) which is likely due to the lifestyle interventions (caloric restriction and exercises) that were required of the participants in STEP. As the pioneer of comprehensive obesity treatment, Calibrate continues to expand access to obesity care through our commercial program. Our proven results combine our lifestyle intervention, accountability coaching, and medication as a tool, not the entire treatment, as part of a larger, comprehensive approach to weight management to ensure that the right members are getting the right treatments at the right time for sustainable results. https://lnkd.in/gM-2xmaK

Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial - Nature Medicine

Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial - Nature Medicine

nature.com

Anne Roefs

Professor of Psychology and Neuroscience of Abnormal Eating at Maastricht University

2mo

When you write 'sustained for up to 4 years', do you mean that they continued taking medication during all those years or did they at some point stop?

Jeroen van der Mark

Bewegings- en voedingswetenschap

2mo

Why is there such a steep decrease and then hits baseline? What is the predominant mechanism?

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Incredible insights on long-term weight management with semaglutide! The combination of GLP medication with lifestyle interventions is truly key to sustainable success. 💡✨

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