Slim-Fast has dropped Whoopi Goldberg from its advertising after the comedian made a sexual joke about George Bush.
The Unilever-owned diet food brand acted after Goldberg made fun of the US president at a Democratic fundraiser at Radio City Music Hall in New York last week.
"We should keep Bush where he belongs," Goldberg said, gesturing at her genitals, "and not in the White House."
Slim-Fast said advertisements featuring Goldberg, who is on the Slim-Fast diet, would be withdrawn.
"We are disappointed by the manner in which Ms Goldberg chose to express herself and sincerely regret that her recent remarks offended some of our consumers," said the Slim-Fast general manager, Terry Olson.
Goldberg accepted the company's decision but said she had criticised presidents of all persuasions. "While I can appreciate what the Slim-Fast people need to do in order to protect their business, I must also do what I need to do as an artist, as a writer and as an American, not to mention as a comic," she told the Bloomberg news wire.
"I've done material on every president in the past 20 years, from Reagan to Carter, from Clinton to Bush. It seems now that people from the other side are using this to further their own agenda."
John Kerry and John Edwards, the Democratic presidential and vice-presidential candidates, attended the event, which raised $7.5m (£4.1m), but they both steadfastly avoided commenting about the joke.
The comedian said earlier that she had refused to let the Democrats pre-vet her material.
"I Xeroxed my behind and I folded it up in an envelope and I sent it back with a big kiss mark on because we're Democrats - we're not afraid to laugh," she said.
Goldberg has been attacked by rightwing American newspapers after her joke.
"Jerky jokester Whoopi in dirty diss at Dubya" was the headline on the story in the New York Post.
"Waving a bottle of wine, she fired off a stream of vulgar sexual wordplays on Bush's name in a riff about female genitalia, and boasted that she'd refused to let Team Kerry clear her material," the paper reported.
· To contact the MediaGuardian news desk email editor@mediatheguardian.com or phone 020 7239 9857
· If you are writing a comment for publication, please mark clearly "for publication".