Attended elementary school on an American Indian reservation in Washington State
Made his Broadway debut in 1993 with Frank Gilroy's play Any Given Day
Breakout role came with his Obie Award-winning turn in the 1995 Broadway production of Love! Valour! Compassion!; made his feature-film debut two years later in the big-screen adaptation
First series-regular role was on the sitcom Jack & Jill, which ran for two season on the WB
Frequently plays wounded characters: In Any Given Day, he's in a wheelchair; in Love! Valour! Compassion!, he's blind; in Angels in America, he's hobbled
Spun off his popular Weeds character, Andy Botwin, into The University of Andy, a series of fake educational shorts
Awards
2008Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated
2007Golden Globe-Best Performance by an Actor in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television:nominated
2006Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated