Buffalo Bills at New Orleans Saints: Live stream, time, date, betting odds, how to watch

By the time the Buffalo Bills and New Orleans Saints kick off on Thanksgiving, millions of turkeys will have been consumed and tryptophan-induced naps will have been taken. 

The holiday's third and final game will feature two teams coming off losses. The Saints (5-5) will likely start Trevor Siemian at quarterback for the fourth straight game, even with Taysom Hill receiving a contract extension Monday, and they might be without running back Alvin Kamara again.

The Bills (6-4) have seen their early-season grip on the AFC East slip away and will look to rectify a poor defensive effort that allowed Indianapolis Colts running back Jonathan Taylor to torch them for five touchdowns. 

Here's everything you need to know to watch Thursday:  

What time does Bills at Saints start? 

Kickoff is Thursday, Nov. 25 at 8:20 p.m. ET from Caesars Superdome in New Orleans. 

NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.

What TV channel is Bills at Saints on? 

The game will be broadcast nationally on NBC. Mike Tirico (play-by-play), Drew Brees (analyst) and Michele Tafoya (sideline reporter) will be on the call. 

How can I watch Bills at Saints online via live stream? 

The game can be streamed on NBCSports.com, through the NBC Sports app and will also be available on Peacock and FuboTV. 

What are the betting odds for Bills at Saints?

Buffalo is favored by 6.5 points and the over/under is 45.5, according to Tipico Sportsbook.   

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