The Boston Red Sox start a mini two-game set against the archrival New York Yankees at 6:35 p.m. Eastern at Yankee Stadium Tuesday. The defending World Series champions took last year's season series 13-10.

Odds provided by FanDuel; for a full-set of today's sports betting odds, access them at USA TODAY Sports.

Boston Red Sox at New York Yankees: Projected Starting Pitchers

Joe Nicholson-USA TODAY Sports

LHP Chris Sale vs. LHP James Paxton

Sale owns a career 1.86 ERA at Yankee Stadium. The 30-year-old lefty has been going through a miserable start to the 2019 campaign, however; as he sports an ERA of 9.00 through his first 13 innings. He has been charged with the loss in each of his first three starts while striking out just 5.54 hitters per nine and issuing his worst walk rate since 2011 at 2.77. Sale's velocity is down on each of his four main pitches and he's allowing more hard contact.

Paxton has started his Yankees tenure with a 6.00 ERA through three starts and 15 innings. He's striking out 11.40 batters per nine but walking 3.60 with an inflated 1.80 homers per nine. His opponent BABIP is a staggering .436 as he's suffered from poor defensive play behind him.

Boston Red Sox at New York Yankees: By the Numbers

• Boston is an all-time 447-640 as the visitor against New York. Its overall record in the head-to-head series is 991-1,189.
• Both teams are 4-6 over their last 10 games and each has just six total wins on the season.
• The Yankees have a team OPS of just .604 against left-handed pitching this season and rank 27th in the league. The Red Sox is 13th at a .769 clip.
• Red Sox OF J.D. Martinez leads the majors with a personal 2.195 OPS against lefties and SS Xander Bogaerts ranks seventh.

Boston Red Sox at New York Yankees: Key Injuries

Red Sox OFs Jackie Bradley Jr. and Andrew Benintendi are both questionable to return to the lineup Tuesday after missing three and one games, respectively.

Yankees C Austin Romine said he's expecting to return to the lineup Tuesday, while Gary Sanchez remains sidelined due to a calf issue. Dellin Betances, Aaron Hicks, Didi Gregorius, Troy Tulowitzki, Miguel Andujar, and Giancarlo Stanton all remain sidelined.

Boston Red Sox at New York Yankees: Picks and Betting Tips

Moneyline: Both teams have -108 odds Tuesday, as they've been equally disappointing thus far. Side with Boston, and its two lefty killers.

Against the spread: With the elevated threat of longballs from Martinez and Bogaerts, back the Red Sox at +150 to cover -1.5.

Over/under: In what should be a battle of aces, we'll opt for the OVER on a run line of 8 with -112 odds, as both Sale and Paxton struggle in the early going.

Follow Esten on Twitter @EstenMcLaren

MORE:

Packers' puzzling goal-line decisions end in disaster

Burmese python discovered in surprising place

Rangers ripped for not catching easy foul ball so pitcher could reach milestone

Gardner Minshew finally got to meet 'Uncle Rico' and NFL fans loved it

See Felix Hernandez's emotional walk off the mound for the Mariners