Boston Red Sox at New York Yankees odds, picks and prediction

The Boston Red Sox (34-23) and New York Yankees (31-27) continue their three-game set Saturday with Game 2 at Yankee Stadium beginning at 7:15 p.m. ET. Let's analyze BetMGM Sportsbook's lines around the Red Sox vs. Yankees odds with MLB picks and predictions.

Boston jumped on Yankees RHP Michael King early Friday with a 3-run blast from 3B Rafael Devers in the top of the first inning. The Yankees were unable to overcome it in their 5-2 loss.

Season series: Red Sox 1-0.

LHP Eduardo Rodríguez takes the rubber for the Red Sox. He is 5-4 with a 5.64 ERA (52 2/3 IP, 33 ER), 1.44 WHIP, 2.2 BB/9 and 9.9 K/9 over 10 starts.

• Last outing: Loss, 11-2, in 4 2/3 IP with 6 ER, 7 H, 2 BB and 4 K at the Houston Astros Monday.
• Career vs. Yankees: 6-6 with a 3.87 ERA (93 IP, 40 ER), 1.41 WHIP and 7.6 K/9 across 16 starts and two relief appearances.
  • vs. Yankees on the current roster: 138 at-bats with a .261/.380/.514 slash line, 40/25 K/BB, 9 HR and 26 RBIs.

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RHP Jameson Taillon makes his 11th start for the Yankees. He is 1-4 with a 5.10 ERA (47 2/3 IP, 27 ER), 1.26 WHIP, 2.8 BB/9 and 10.4 K/9.

• Last outing: Loss, 3-1, in 5 IP with 3 ER, 5 H, 3 BB and 5 K against the Tampa Bay Rays Monday.
• Career vs. Red Sox: No-decision in 7 IP with 0 ER, 5 H, 3 BB and 6 K in the Pittsburgh Pirates' 3-0 loss in April 2017. Taillon pitched for the Pirates from 2016-19 and he missed all of 2020.
  • vs. Red Sox on the current roster: 19 at-bats with a .368/.400/.895 slash line, 7/0 K/BB, 2 HR and 5 RBIs.

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Red Sox at Yankees odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:50 a.m. ET.

• Money line: Red Sox +105 (bet $100 to win $105) | Yankees -125 (bet $125 to win $100)
• Against the spread/ATS: Red Sox +1.5 (-190) | Yankees -1.5 (+155)
• Over/Under: 9 (O: -120 | U: +100)

Prediction

Yankees 5, Red Sox 4

Money line (ML)

BET the YANKEES (-125) for 1 unit because Rodríguez was terrible in May and hasn't pitched well on the road this season.

He was 1-4 in May with a 7.28 ERA and has a 6.42 road ERA and 1.72 road WHIP compared to a 4.26 ERA and 0.95 WHIP in Boston.

Furthermore, Rodríguez's opponents in away games have a .338 batting average and .896 OPS. His home opponent's batting average sits at .222 with a .702 OPS.

Rodríguez's stuff hasn't been as sharp in previous years; his whiff rate is the lowest it's been since his rookie season and his meatball rate is the highest.

Boston's 5-2 win Friday in Yankee Stadium snapped an 11-game losing skid to the Yankees in New York and I think the Yankees get back to their winning ways against their long-time rival.

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Run line/Against the spread (ATS)

PASS because New York's lineup has been the most disappointing unit in the majors this season and certainly hasn't hit well enough to justify laying the run and a half with the Yankees.

Over/Under (O/U)

PASS with a slight "lean" to the UNDER 9 (+100) because of New York's aforementioned struggles at the plate and the market is overwhelmingly backing the Over so there's a "fade the market" angle in Red Sox-Yankees.

Moreover, any signs of trouble from each team's starter should get the bullpens fired up. Both relief units are top-10 in WAR, xFIP, SIERA and left-on-base percentage.

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