Cleveland Indians at Minnesota Twins odds, picks and prediction

The Cleveland Indians (40-31) open a four-game series on the road Thursday against the AL Central rival Minnesota Twins (31-42). First pitch is set for 8:10 p.m. ET at Target Field. Let's analyze BetMGM Sportsbook's lines around the Indians vs. Twins odds with MLB picks and predictions.

RHP J.C. Mejia is the projected starting pitcher for the Indians. The rookie is 1-2 with a 6.11 ERA, 1.25 WHIP, 8.2 K/9 and 2.5 BB/9 in 17 2/3 IP over 4 starts and 3 relief appearances.

Mejia is making his fourth start on the road already after entering the rotation at the beginning of the month. He gave up 6 ER on 7 H in 5 IP in his last outing at Pittsburgh.

RHP Jose Berrios is the projected starting pitcher for the Twins. He is 7-2 with a 3.56 ERA, 1.09 WHIP, 9.4 K/9 and 2.3 BB/9 in 83 1/3 IP over 14 starts.

The Twins have won his last seven starts. He allowed 2 ER on 5 H and 1 BB in 5 2/3 IP in a 5-3 loss at Cleveland on April 26.

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Indians at Twins odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 10:10 a.m. ET.

• Money line : Indians +150 (bet $100 to win $150) | Twins -185 (bet $185 to win $100)
• Against the spread/ATS : Indians +1.5 (-130) | Twins -1.5 (+105)
• Over/Under : 9 (O: -110 | U: -110)

Prediction

Twins 6, Indians 4

Money line (ML)

The Indians have won eight of their last 12 games are 20-18 on the road, but are 2-3 on their current road trip. They've yet to pick up a victory in Mejia's previous three starts away from Cleveland.

The teams meet for the first time in Minnesota after splitting the first six games of the season series in Cleveland.

The Twins have won five of their last six games and have not lost with Berrios on the mound since May 8. They are 5-1 at home in Berrios starts.

Take the TWINS (-185).

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Run line/Against the spread (ATS)

Cleveland is 36-35 ATS this season and 21-17 ATS on the road. They have covered the spread in only four of their last 11 games, and are 0-4 ATS in Mejia's starts.

Minnesota has the league's lowest overall cover percentage at 35.6% and the lowest at home at 29.7%. However, Berrios on the mound changes things- they're 7-7 ATS in his starts.

Take the TWINS -1.5 (+105).

Over/Under (O/U)

63.9% of the games at Target Field this season have gone Over the projected total. Seven of Berrios' last nine starts have had totals of at least nine runs.

The Indians are 39-30-2 O/U this season and the Twins are 46-24-3 O/U.

Take OVER 9 (-110).

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