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NFL

Kansas City Chiefs at Arizona Cardinals odds, picks and prediction: Murray vs. Mahomes on display

Jess Root
Sportsbook Wire

The Kansas City Chiefs (1-0) face the Arizona Cardinals (1-0) Friday at State Farm Stadium. Kickoff is scheduled for 8 p.m. ET. Below, we look at the Chiefs at Cardinals odds and lines.

The Chiefs only played their starters for a couple of series against the San Francisco 49ers in their opener as the backups rallied to score the game-winning touchdown with just over a minute remaining in a 19-16 victory. The 49ers took at 16-13 lead with 2:37 left in the fourth quarter but the Chiefs went 68 yards in nine plays in 1:23 to secure the win.

The Cardinals picked up a 19-16 preseason win at home over the Dallas Cowboys in their opener. K Matt Prater hit two field goals in the final two minutes including a 47-yarder as time expired.

Chiefs at Cardinals: Odds, spread and line

Odds via Tipico Sportsbook; access USA TODAY Sports' betting odds for a full list. Lines last updated Monday at 8 p.m. ET.

NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.

  • Money line: Chiefs -133 (bet $133 to win $100) | Cardinals +110 (bet $100 to win $110)
  • Against the spread/ATS: Chiefs -2.5, -115 (bet $115 to win $100) | Cardinals +2.5, -105 (bet $105 to win $100)
  • Total: 41.5, Over -105 (bet $105 to win $100) | Under -115 (bet $115 to win $100)

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2020 Betting stats:

  • ATS : Chiefs 8-11 | Cardinals 7-9
  • O/U : Chiefs 9-10 | Cardinals 5-11

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The Cardinals, at +110 odds, have an implied 47.62% chance of winning, or 11/10 fractional odds. If Arizona wins outright, ties, or loses by less than a field goal a Cardinals +2.5 (-105) ATS bet wins.

The Chiefs (-133) have an implied 57.08% chance of beating the Cardinals, or 100/133 fractional odds. Kansas City must win by 3 or more points for a Chiefs -2.5 (-115) ATS ticket to cash.

There would need to be at least 42 points scored Friday for an Over 41.5 (-105) ticket to cash, while a combined point total of 41 or fewer points is a win for the Under.

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