2022 Cook Out Southern 500 odds, picks and predictions

The NASCAR Cup Series playoffs begin at Darlington Raceway Sunday night for the 2022 Cook Out Southern 500. The green flag is set to drop a little after 6 p.m. ET (USA Network). Below we analyze the 2022 Cook Out Southern 500 odds and lines, with NASCAR picks and predictions.

Sunday's race is scheduled for 367 laps and 501.3 miles on the 1.366-mile oval for the Sprint Cup Series playoff opener. The Cook Out Southern 500 is the 2nd stop of the season at Darlington.

2022 Cook Out Southern 500: What you need to know

• Penske Racing's Joey Logano registered the victory at the Goodyear 400 in the 1st Darlington stop of the season May 8.
• Joe Gibbs Racing's Denny Hamlin leads all active drivers with 4 Darlington victories. He leads everyone with a 7.8 Average Finish Position (AFP) in 20 Cup starts.
• Ford and Toyota have dominated at Darlington in recent seasons, with Toyota posting 7 wins across the past 11 starts, and Ford taking the other 4.
• Chevrolet hasn't been to Victory Lane at "The Track Too Tough To Tame" since Kevin Harvick picked up checkers April 12, 2014.
• Harvick has 3 wins, 13 top-5 finishes, 18 top-10 runs in 29 Cup starts at Darlington. His 813 laps led is tops among active drivers.

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