NFL

First look: Indianapolis Colts at Jacksonville Jaguars odds and lines

Andrew Reid

Sportsbook Wire

The Indianapolis Colts (0-0-1) head to TIAA Bank Field to face the Jacksonville Jaguars (0-1) in Week 2 action. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we look at Colts vs. Jaguars odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts entered the 4th quarter of their season opener at the Houston Texans down 20-3, but rallied to tie the game and force overtime. However, PK Rodrigo Blankenship missed a 42-yard attempt in extra time to secure the victory and when the dust settled things were still all square.

QB Matt Ryan was 32-for-50 for 352 yards with 1 TD and 1 INT in his Indy debut. RB Jonathan Taylor, who led the league in rushing yards last season, had 161 yards on 31 carries. Breakout star WR Michael Pittman Jr. added 121 yards on 9 catches, including the teams' final TD.

Also see: All Week 2 odds and lines

The Jaguars had a 2nd half rally of their own, but they let a small lead disappear in the final 2 minutes of play as they fell 28-22 at the Washington Commanders.

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Second-year QB Trevor Lawrence (24-for-42, 275 yards, 1 TD, 1 INT) clicked with new WR Christian Kirk. The former Arizona Cardinal, the big free-agent signing for the Jags, led all receivers with 117 yards on 6 catches from 12 targets. RB James Robinson paced the backfield with 11 carries for 66 yards and 1 TD.

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Colts at Jaguars odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:49 a.m. ET.

Money line (ML): Colts -205 (bet $205 to win $100) | Jaguars +170 (bet $100 to win $170)
Against the spread (ATS): Colts -4.5 (-105) | Jaguars +4.5 (-115)
Over/Under (O/U): 45.5 (O: -115 | U: -105)

2022 betting stats

ML : Colts 0-0-1 | Jaguars 0-1
ATS : Colts 0-1 | Jaguars 0-1
O/U : Colts 0-1 | Jaguars 1-0

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Colts vs. Jaguars head-to-head

These teams played twice before they became divisional rivals in 2002, and they've met twice a season since. Indianapolis holds a 26-16 edge in the all-time series. The Jaguars have finished last in the AFC South for the last 4 years, but they've still split their 8 meetings with Indy.

Jacksonville won just 3 games in Lawrence's rookie season at the helm, but one of them was a 26-11 Week 18 home victory over Indy that resulted in the Colts missing the postseason. The Jags have covered the spread in 4 straight meetings and the last 3 games between these teams have gone Under.

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