Sweet 16 first look: Princeton vs. Creighton odds, lines and trends

The 15th-seeded Princeton Tigers (23-8) will face the 6th-seeded Creighton Bluejays (23-12) Friday in a South Region matchup. Tip-off from the KFC Yum! Center in Louisville is set for 9 p.m. ET (TBS). Below, we look at Princeton vs. Creightonodds from Tipico Sportsbook. Plus, check out our expert college basketball picks and predictions.

Princeton is coming into this game following a 78-63 thrashing of the No. 6 Missouri Tigers in the Round of 32. It beat No. 2 Arizona 59-55 in the Round of 64. Princeton made the tournament with 2 wins in the Ivy League Tournament, taking down Yale 74-65 in the final. The Tigers are 4-0 against the spread (ATS) in their 4 postseason games.

Creighton took down No. 3 Baylor 85-76 in the Round of 32 following a 72-63 win over No. 11 NC State, covering both games as a 1.5-point and 5.5-point favorite. They are 3-1 ATS in their 4 postseason.

Creighton ranks No. 22 in the USA TODAY Sports Coaches Poll