Sweet 16 first look: San Diego State vs. Alabama odds, lines and trends

The 5th-seeded San Diego State Aztecs (29-6) will battle the No. 1 seed Alabama Crimson Tide (31-5) in the Sweet 16 of the South Region Friday. Tip from KFC Yum! Center is set for 6:30 p.m. ET (TBS). Below, we look at San Diego State vs. Alabamaodds from Tipico Sportsbook. Plus, check out our expert college basketball picks and predictions.

San Diego State cemented its spot in the Sweet 16 with a convincing 75-52 win over 13-seed Furman on Saturday to cover as a 4.5-point favorite. Four players scored in double digits led by G Micah Parrish who had 16 points. The Aztecs took down upset-favorite Charleston 63-57 in the first round as 5.5-point favorites on Thursday.

San Diego State is an impressive 4-1 against the spread (ATS) in its last 5 postseason games - 2 in the NCAA Tournament and 3 in the Mountain West Tournament - with the Under hitting in each of the 5 games.

Alabama took down Maryland on Saturday 73-51 to cover as an 8-point favorite. While it started slow, only scoring 28 points at the half, it put up 45 in the 2nd half to pull away. The Crimson Tide were led with 21 points from G Jahvon Quinerly and 19 from F Brandon Miller, a massive turnaround from his 0-point showing as the Tide steamrolled 16-seed Texas A&M-CC 96-75, but failed to cover as 24-point favorites.