Chicago White Sox at Houston Astros odds, picks and predictions

The Chicago White Sox (1-0) take on the Houston Astros (0-1) Friday in the 2nd game of a 4-game season-opening series at Minute Maid Park. First pitch is at 8:10 p.m. ET (MLB Network). Let's analyze Tipico Sportsbook's lines around the White Sox vs. Astrosodds and make our expert MLB picks and predictions for the best bets.

Season series: White Sox lead 1-0

The White Sox defeated the Astros 3-2 on Thursday with RHP Dylan Cease allowing only 1 ER while fanning 10 in 6 1/3 IP. RHP Reynaldo Lopez got the save as Chicago looks to replace closer Liam Hendriks, who is undergoing cancer treatment.

The World Series champions got a solid outing from LHP Framber Valdez on Thursday with 4 K and 0 ER in 5 IP while OF Yordan Alvarez homered in the 9th inning.

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