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Pompeo's final episode will be titled "I'll Follow the Sun."
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The actress also dished on her fight for equal pay.
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"I am eternally grateful and humbled by the love and support you have all shown me," Pompeo wrote.
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Here's when you'll be able to watch the next new episode of Grey's Anatomy.
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The fall finale airs tonight on ABC.
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Williams can’t seem to say goodbye.
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We have a medical emergency - Grey's is back on!
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The long-running medical drama first debuted all the way back in March of 2005 on ABC.
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Pompeo will only be featured in eight episodes of Grey's as she works on a new series titled Orphan.
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Whether you want a good laugh or something moody to help you wallow, we've got you covered with the top titles to stream when you're down in the...
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Doc, I got a bad case of the streaming blues.
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Doctor, doctor, give me the news; I got a bad case of lovin' Grey's.
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The latest season of Grey's Anatomy is coming to Netflix!
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The next new episode of Grey's Anatomy is just around the corner.
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Here's when you can stream the next new episode of this long-running ABC medical drama!
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There's never a dull moment at Grey Sloan Memorial.
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Time to pick up on that literal cliffhanger.
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Krista Vernoff will also return as showrunner of the series.
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It wouldn't be a Grey's Anatomy midseason finale without some love triangle drama.
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Winners included Keeping Up With the Kardashians, Loki, Olivia Rodrigo, and more.