Centuries of colonialism have left lingering inequities in science. But researchers around the world are working together to shift the axis of scientific influence, bringing scientists of the Global South into the spotlight and building a more equitable research enterprise. Learn more this week in Science: https://scim.ag/7XM
Science Magazine
Book and Periodical Publishing
Washington, DC 332,905 followers
The world's leading outlet for scientific news, commentary, and cutting-edge research.
About us
Founded in 1880 on $10,000 of seed money from the American inventor Thomas Edison, Science has grown to become the world's leading outlet for scientific news, commentary, and cutting-edge research, with the largest paid circulation of any peer-reviewed general-science journal. Through its print and online incarnations, Science reaches an estimated worldwide readership of more than one million. In content, too, the journal is truly international in scope; some 35 to 40 percent of the corresponding authors on its papers are based outside the United States. Its articles consistently rank among world's most cited research.
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http://www.science.org
External link for Science Magazine
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- Book and Periodical Publishing
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- 51-200 employees
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- Washington, DC
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Science Magazine reposted this
Did you hear the rumbles?? It came from the deep(ish) ocean... and then transitioned to a euryhaline lifestyle causing widespread fish-killing blooms in brackish water throughout Texas and Europe... It's Prymnesium parvum and their #PKZILLA s! Thrilled that our work is out today in Science Magazine : https://lnkd.in/gwaKZK3j . Lessons learned below: Never heard of Prymnesagum pardum or a PKZILLA and wondering why to care? Fear not! P. parvum are a species of single-celled marine & brackish water algae, that make giant (90+ carbon) fatty-acid like toxins called prymnesins. These algae & toxins cause massive environmental fish-kills. You may have heard of the 2022 Oder river environmental disater in Europe: P. parvum was to blame! We aimed to discover the genes behind the prymnesin toxins, to better control these fish-kills, and since prymnesin is also structurally related to "red-tide" toxins - to better understand those human-health impacting toxins. We found the PKZILLAs, unprecedentedly large genes, and through detailed analysis, concluded they must be causal to make the prymnesins. We wanted to do explicit genetic and biochemical experiments to validate this, but couldn't, because they're really challenging! One does not simply express a largest known protein. So, to cross-validate this claim, we turned to the natural laboratory, and investigated the "B-type" Prymnesium parvum PKZILLAs. B-type P. parvum make a slightly shorter prymnesin backbone. And, B-type PKZILLA, PKZILLA-B1, aligned very well to the B-type prymnesin backbone! With that, we could be confident we had found a nugget of truth with the PKZILLAs, that they were causal for prymnesin biosyntheis. The other major claim, with some caveats, is PKZILLA-1 is the new largest known protein. PKZILLA is clearly larger than human titin, the long-standing largest known protein, and seemingly the new largest known eukaryotic protein. But giant bacterial genes (up to >85,000 residues; https://lnkd.in/gFKEvQu4), and single molecule study of "infinite" proteins translated in vitro off circular RNAs (~26,000 residues on average; https://lnkd.in/gQt-Qer3), and "nearly-endless" proteins produced by the bacterial DRT virus defense system (https://lnkd.in/gjEPPszV) could challenge PKZILLA-1's (~45,000 residue) size. In short, plenty of fun experiments to come! What's next for us? If anyone has tips for CRISPR in haptophytes (never been done?) or tips for ultra-sensitive separations of proteins of unprecedented size, I'd love to get in touch! Many thanks to team: Vikram Shende, @igorwierzbicki (UC San Diego), @robertauber (Purdue University), @davidgonzalez (UC San Diego), @jenniferwisecaver (Purdue University), @BradMoore (Scripps Institution of Oceanography) plus critical PKZILLA-B1 contributions from @amandapendletonhoskins, @nathanwatervoort. A giant problem? Not for this team!
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A book by Philipp Dettmer, creator of the YouTube channel Kurzgesagt (German for “in a nutshell”), charts the vast array of different immune cells, what they do, the way they communicate with each other, and what happens when things go wrong. Check out the Science Books Review on #BookLoversDay: https://scim.ag/7YA
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Drawing the mind, one neuron at a time. A 2022 book walks readers through the life and work of Santiago Ramón y Cajal, the Spaniard whom many consider the founder of modern neuroscience. Check out the Science Books Review on #BookLoversDay: https://scim.ag/7Yp
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In marine mammals and birds—which need to sleep, breathe, and avoid predators—diverse neurophysiological, respiratory, and behavioral solutions to these ecological challenges have evolved. Learn more in a 2023 #SciencePerspective: https://scim.ag/7XY #ScienceMagArchives
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Science Magazine reposted this
It might not be as hard as we thought to make Mars more habitable—just a sprinkle of iron and aluminum glitter. That story and more of the best from Science Magazine and science in this edition of #ScienceAdviser: https://lnkd.in/ggDWW2mQ
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Tuna (or any seafood for that matter) is an odd favorite for cats—an animal that evolved in the desert. On #InternationalCatDay, explore the research that may give a biological explanation for this curious craving. https://scim.ag/7XJ
Why do cats love tuna so much? Scientists may finally know
science.org
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Not only do catnip and silver vine hold a special place in felines’ hearts, the intoxicating chemicals in these plants also protect cats from mosquito bites, according to research from Science Advances. Learn more on #InternationalCatDay: https://scim.ag/7Xv
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Science Magazine reposted this
New research suggests Flores' tiny people survived for millennia alongside full-size human–eating dragons. Why'd they disappear? Perhaps even the hobbit couldn’t compete with the kingdom of men. That and more of the best from Science Magazine and science in this edition of #ScienceAdviser: https://lnkd.in/gaWdpWdk
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Researchers have developed a novel approach to #3Dprinting they call “CLEAR,” which significantly improves the strength and durability of materials by using a combination of light and dark chemical reactions to create densely entangled polymer chains. Learn more in Science: https://scim.ag/7WN