When Dr. Tiffany M. Osborn received her COVID-19 vaccination shortly after vaccines became available in late 2020, she felt hopeful about the pandemic's trajectory. A year later, she's sad and frustrated to see so many COVID patients in the ICU. Matt Miller / Washington University School of Medicine hide caption
An public safety message from the government of South Africa. The country announced on Thursday that it was past the peak of its latest coronavirus surge. South African Government/Twitter hide caption
A colorized electron micrograph image of a cell (red) infected with with SARS-CoV-2 virus particles (yellow), isolated from a patient sample. Science Source hide caption
Trucks drive in front of Teva Pharmaceutical Logistic Center in the town of Shoam, Israel, on Oct. 16, 2013. On Thursday, a jury held Teva responsible for contributing to the opioid crisis. Dan Balilty/AP hide caption
Car keys are shown by glasses with alcohol in this stock photo illustration. Companies are developing technology that would allow cars to stop people from driving when drunk. Peter Dazeley/Getty Images hide caption
Victoria Gray, who has sickle cell disease, volunteered for one of the most anticipated medical experiments in decades: the first attempt to use the gene-editing technique CRISPR to treat a genetic disorder in the United States. Meredith Rizzo/NPR hide caption
Health care workers administer COVID-19 tests at a drive-through clinic in Sydney, Friday, Dec. 31. Australian health authorities have reported a record 32,000 new virus cases, many of them in Sydney. Bianca De Marchi/AP hide caption
The Carnival Cruise Line's Carnival Sunrise ship is seen in the port of Miami on Dec. 23, 2020, amid the coronavirus pandemic. Daniel Slim/AFP via Getty Images hide caption
A 8-year-old looks out her bedroom window during self-quarantine with her family due to COVID-19. John Moore/Getty Images hide caption
The top Fresh Air web stories of 2021 reflect the show's status as a place where artists, authors and journalists speak to the moment. Valerie Macon/AFP; Grace Cary; Chip Somodevilla/Getty Images hide caption
Activists participate in a candlelight vigil calling for an end to the nation's opioid addiction crisis at the Ellipse in Washington, D.C., in August 2017. Alex Wong/Getty Images hide caption
A health care worker holds doses of J&J vaccines at the Gandhi Phoenix Settlement in Bhambayi township, South Africa, on Sept. 24. A study of the J&J booster shot in the country had promising results against the omicron variant. Rajesh Jantilal/AFP via Getty Images hide caption
Women wearing masks to help curb the spread of the coronavirus walk against cold strong winds in Beijing, China, Thursday, Dec. 30, 2021. Ng Han Guan/AP hide caption